Less frenetic, slower paced and (with a few exceptions) less crowded than e.g. La Paz.
The most obvious symbol of the city to the visitor is Christo de la Concordia, a large statue of Jesus above and overlooking the city. The statue itself is slightly higher and slightly larger that its “equivalent” in Rio de Janeiro, making it the largest statue of Jesus in the world, at least until 2010 when Poland made a larger one. But the site does have amazing views over the city.
Generally the city feels safe, certainly north of Calle Aroma. Some guides warn of gangs south of Calle Aroma and personal experience is that these gangs do exist (though in personal experience caused no problems).
For other South American posts see South America Map.